PHILADELPHIA — The Philadelphia Eagles suffered another potentially damaging injury blow Sunday night when running back and punt returner Darren Sproles injured his knee in a 27-0 win over the New York Giants.

According to coach Chip Kelly, Sproles suffered an MCL sprain in his left knee. He said it wasn’t nearly as severe as guard Evan Mathis’ MCL sprain, but he was vague about how long he thinks Sproles might be out.

“We’ll see how long it’s going to be,” he said. “It could be a week or two. He could be back after (the bye). We have a week off. He’ll get treatment and we’ll assess him when we get back next Tuesday.”

Mathis, the Eagles’ All-Pro left guard, sprained his right MCL in the season opener. He was placed on short-term injured reserve and will be eligible to be activated in Week 10.

It’s not as serious as Mathis’ injury, “from what I understand,” Kelly said. “Evan’s out for eight weeks. It doesn’t sound like it will be that long (with Sproles). I talked to Darren after the game and he didn’t think it was anything big. It doesn’t sound like it will be that long.”

At the moment, the Eagles have only one healthy running back, LeSean McCoy. Their third running back, Chris Polk, is out indefinitely after reinjuring his hamstring.

The Eagles have their bye this week and then travel to Arizona to play the Cardinals on Oct. 26. If Sproles can’t play against the Cardinals, the Eagles will need to add a running back.

The most likely candidate is Matthew Tucker, who is on the team’s practice squad.

Sproles is averaging 6.6 yards per carry. He had a 15-yard touchdown run in Sunday’s win over the Giants.

He’s also second in the league in punt returns with a 15.6-yard average. He had a 43-yard return Sunday before getting hurt.

If Sproles can’t play against the Cardinals, the Eagles have several potential punt return candidates, including rookie wide receiver Josh Huff.

NOTES: Linebacker Mychal Kendricks missed the last three games with a calf injury and may return to practice next week. … Wide receiver Josh Huff got a season-high 22 offensive snaps in Sunday’s win over the Giants.

REPORT CARD V. GIANTS

–RUSHING OFFENSE: A-plus — LeSean McCoy finally got untracked. He notched his first 100-yard rushing game of the season, rushing for 149 yards on 22 carries against the Giants. Darren Sproles had a 15-yard touchdown run. McCoy came into the game averaging just 2.3 yards per carry out of two-tight end sets and gained 61 on six carries.

–PASSING OFFENSE: B — Nick Foles had two really bad-looking interceptions and very nearly had a third. He was only 4-for-9 on third down. Tight ends Zach Ertz, Brent Celek and James Casey combined for eight catches for 118 yards and two touchdowns. Riley Cooper had five catches in the first half.

–RUN DEFENSE: A-minus — The Eagles’ front seven dominated the Giants’ offensive line and shut down running back Andre Williams, holding him to 25 yards on 10 carries in the first half. The Giants averaged just 3.7 yards per carry.

–PASS DEFENSE: A — The Eagles had a perfect storm of excellent coverage and a fierce pass rush. They sacked Eli Manning six times and held him to 151 yards and zero touchdown passes. Linebacker Connor Barwin had one of his best days as a pro with three of the six sacks of Manning.

–SPECIAL TEAMS: A-plus — Darren Sproles had a 43-yard punt return, helped by a big block by Trey Burton. Chris Maragos partially blocked a punt by Steve Weatherford. Cody Parkey hit both of his first-half field goal attempts, including a 45-yarder, and had touchbacks on four of six kickoffs.

–COACHING: A — Bill Davis mixed up his coverages and blitzes and cooled off red-hot Giants quarterback Eli Manning. Chip Kelly finally got the running game going with a little help from Giants defensive coordinator Perry Fewell, who played nickel almost the entire game.