ARLINGTON, Texas — Last summer during training camp, Philadelphia Eagles running back LeSean McCoy proclaimed, “I own Dallas.”

On Thursday, he went to work ruining Dallas Cowboys owner Jerry Jones’ Thanksgiving.

McCoy rushed for 159 yards and scored the clinching touchdown midway through the third quarter as Philadelphia seized first place in the NFC East with a 33-10 victory over Dallas at AT&T Stadium.

The Cowboys were trying to stay in the game when Philadelphia faced a second-and-5 from the Dallas 38 with 7:29 left in the third quarter. McCoy found running room through the right side, shook off Cowboys cornerback Orlando Scandrick in the secondary and dashed the rest of the way for a 38-yard touchdown that put the Eagles ahead 30-10.

The Philadelphia defense took over there, sacking Cowboys quarterback Tony Romo twice on the ensuing drive. Eagles cornerback Cary Williams intercepted a Romo pass to end the drive and keep momentum with Philadelphia (9-3).

Eagles quarterback Mark Sanchez improved to 4-1 since replacing injured Nick Foles as the starter. Foles was hurt in the first quarter at Houston on Nov. 2, and Sanchez since led Philadelphia to wins over the Houston Texans, Carolina Panthers, Tennessee Titans and now Dallas.

Sanchez completed 20 of 29 passes for 217 yards and a touchdown with no interceptions against the Cowboys (8-4).

Romo and the Cowboys couldn’t keep up. Romo finished 18-for-29 for 199 yards with two interceptions and no touchdowns. Dallas couldn’t get DeMarco Murray loose either, as the star running back finished with 73 yards on 20 carries.

McCoy and Sanchez powered the Eagles to a 14-0 lead before the Cowboys could answer.

McCoy ignited Philadelphia’s game-opening scoring drive with a 36-yard run to the Dallas 22. Sanchez then completed three passes to move the Eagles inside the Cowboys 10-yard line and took it himself for a 2-yard touchdown run.

Sanchez hit wide receiver Jordan Matthews for a 27-yard touchdown for the second score, capping an 88-yard march.

Dallas finally answered with Murray’s 1-yard touchdown run on the first play of the second quarter, finishing a 67-yard drive. Romo hit wide receiver Dez Bryant for the key play of the drive, a 38-yard gain to the Philadelphia 4.

Philadelphia threatened to run away with it in the second quarter but instead settled for three field goals on three drives inside the Dallas 20. Cody Parkey kicked field goals of 31, 22 and 26 yards.

The Eagles led 23-7 at halftime after outgaining Dallas, 292 yards to 130. Philadelphia finished the game with a 464-267 edge in total yards.

NOTES: The Cowboys need one more victory to guarantee their first winning season since 2009. … Dallas QB Tony Romo entered the game on a hot streak despite sustaining a fracture in the transverse processes in his lower back earlier this season. Romo completed 38 of 53 passes for 767 yards, seven touchdowns and no interceptions in the two games leading up to the Thanksgiving Day contest. … The Philadelphia Daily News quoted a source saying injured QB Nick Foles will have his collarbone injury re-evaluated with a CT scan Friday. Foles was injured Nov. 2 at Houston and was expected to be out six to eight weeks.